Effect of Scoparia dulcis (Linn.) and Aerva lanata (Linn.) whole plant and fruit part extracts on urine volume of ethylene glycol induced urolithiasis in male albino rats

Kidney stone is a ubiquitous disease afflicting mankind and it continuous to pose a universal health problem. It is a complex multifactorial disease resulting from an interaction between environmental and genetic factors (Aggarwal et al., 2000). Nearly 4-15% of human populations are suffering from urinary stone problem all over the globe and 80% of them are men between the ages of 20 and 50 years (Chauhan et al., 2008). Areas of high incidence of urinary calculi include the British Isles, Scandinavian countries, Northern Australia, Central Europe, Northern India, Pakistan and Mediterranean countries. In India, 12% of the population is expected to have urinary stones, out of which 50% may end up with loss of kidneys or renal damage (Mohamed et al., 2009).